Skip to content
Tags give the ability to mark specific points in history as being important
  • v1.1.0
    Feature release "T. rex"
    
    New features
    * Support analysis of T cell receptor (TCR) sequences [note 1]
      [74dd84c, 4466259, eed9846, df525df, 3b5ef5e, de94039, b1fedb7,
      53c1a86, 4450917]
    
    Enhancements
    * Accelerate read mapping [eed9846]
    * Accelerate quality control tag statistics [3b67562]
    * Add support for 96x96 (9.0ki) matrix size [72e19a0]
    
    Bugfixes
    * Fix compatibility with new MySQL server mode [6ac6c8d, 3243025]
    * Fix import of IgBLAST productivity status [70009cb]
    * Fix parsing of IgBLAST region information [f6054e2]
    * Fix import of metainformation table [4cdf8cd]
    * Fix parsing of config file by spatials module [45e3a01]
    
    Notes
    [1] Currently only the analysis of TCR alpha/beta chain sequences
    is supported, gamma/delta is still pending
    
  • v1.0.2
    Bugfix release, some enhancements
    
    Bugfixes
    - Fix use of regular expressions for CDR3 identification
    - Fix insertion of IgBLAST score and E-values into the database
    - Fix loss of sequences with long CDR3 and a mutated end-of-CDR3
      motif [note 1]
    - Fix tag correction routine for large mouse matrix
    - Fix handling of empty lines in metadata file
    
    Enhancements
    - More economic handling of database connections (includes time-outs)
    - Remove unused (and unsafe) authentication options
    - Add alternative CDR3 motifs to config
    - Add script for repetitive testing of pipeline
    - Further unification of log output
    
    Notes
    [1] Previous maximum length of CDR3 was 22 amino acids [aa],
    otherwise the a assignment would fail if (and only if) an
    alternative end-of-CDR3 motif was used by a sequence. This length
    limit has now been extended (CDR3 plus J sequence 155 bp). Note
    that IgBLAST currently (version 1.4.0) has a hard-coded maximum
    V_end to J_start distance of 89 bp, which should constitute the
    lower limit of the two.
    
  • v1.0.1
    Bugfix release, some minor enhancements
    
    Bugfixes
    * Fix instable makefile behavior [05c0b1d]
    * Fix incompatibility with current RazorS version [f15a73c]
    * Fix issues with concurrent data processing [fa76ec2]
    * Fix path for metainfo tempate [6092a6d]
    * Fix QC handling of missing locus [8c5f17c]
    * Fix metadata table for Sanger sequences [18acb35]
    * Fix pipeline_status query [4e0b654]
    * Fix subregion identification for truncated sequences [e2d673e]
    * Fix log blob overflow for Sanger metadata import [83a68a7]
    
    Enhancements
    * Adapt invocation of Sanger sequence processing to that of Matrix PCR data [18acb35]
    * Add support for 72x64 (4.5ki) matrix size [2764486]
    * Add log_level-aware logging for mutation identification module [92333f5]
    
  • v1.0.0
    first productive release